Regulation of Yeast-to-Hyphae Transition in Yarrowia lipolytica
نویسندگان
چکیده
منابع مشابه
Roles of the three Ras proteins in the regulation of dimorphic transition in the yeast Yarrowia lipolytica.
Ras proteins in the budding yeast Saccharomyces cerevisiae are essential for growth and dimorphic transition. The dimorphic yeast Yarrowia lipolytica is distantly related to S. cerevisiae. Its genome encodes three Ras proteins. Here, we show that the three Ras proteins in Y. lipolytica are critical for dimorphic transition but are dispensable for growth. Among the three Ras proteins, YlRas2 pla...
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The dimorphic yeast Yarrowia lipolytica is used as a model to study fungal differentiation because it grows as yeast-like cells or forms hyphal cells in response to changes in environmental conditions. Here, we report the isolation and characterization of a gene, ZNC1, involved in the dimorphic transition in Y. lipolytica. The ZNC1 gene encodes a 782 amino acid protein that contains a Zn(II)2C6...
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To develop a direct microbial sugar conversion platform for the production of lipids, drop-in fuels and chemicals from cellulosic biomass substrate, we chose Yarrowia lipolytica as a viable demonstration strain. Y. lipolytica is known to accumulate lipids intracellularly and is capable of metabolizing sugars to produce lipids; however, it lacks the lignocellulose-degrading enzymes needed to bre...
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The oleaginous yeast, Yarrowia lipolytica, is becoming increasing popular for metabolic engineering applications. Advances in synthetic biology and metabolic engineering have allowed microorganisms such as Y. lipolytica to be tailored for specific chemical production. Significant progress has been made to understand the genetics of Y. lipolytica and towards developing novel genetic engineering ...
متن کاملProtein expression and secretion in the yeast Yarrowia lipolytica.
Strains and vectors for protein expression and secretion have been developed in the yeast Yarrowia lipolytica. Host strains were constructed with non-reverting auxotrophic markers, deletions of protease-encoding genes, and carrying a docking platform. To drive transcription, either the synthetic hp4d or the inducible POX2 promoter were used. Protein secretion is either directed by the targeting...
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ژورنال
عنوان ژورنال: mSphere
سال: 2018
ISSN: 2379-5042
DOI: 10.1128/msphere.00541-18